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	<title>Medical blog &#187; Drug</title>
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		<title>Drug recommended to prevent prostate cancer in some older men</title>
		<link>http://www.raganvirtualworkshops.com/21044.php4</link>
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		<pubDate>Mon, 23 Feb 2009 04:07:14 +0000</pubDate>
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		<description><![CDATA[The panel stopped short of recommending that all men take the drug because clinical trials have not yet shown that it reduces deaths.
 Prostate cancer is the second-leading cause of cancer deaths among men, behind lung cancer, with 186,000 new cases diagnosed and 28,660 deaths each year.
 Finasteride is used in low doses under the [...]]]></description>
			<content:encoded><![CDATA[<p>The panel stopped short of recommending that all men take the drug because clinical trials have not yet shown that it reduces deaths.<br />
 Prostate cancer is the second-leading cause of cancer deaths among men, behind lung cancer, with 186,000 new cases diagnosed and 28,660 deaths each year.<br />
 Finasteride is used in low doses under the brand name Propecia as an anti-balding drug and in higher doses under the name Proscar for shrinking enlarged prostate<span id="more-21044"></span> glands. The dose recommended for cancer prevention is the same dosage used in Proscar.<br />
 The drug interferes with the production of male hormones, starving the tumors of fuel they need to grow.<br />
 A major clinical trial reported in 2003 showed that finasteride reduced the risk of prostate cancer by about 25% in men who took it, preventing about 15 cases in every 1,000 men. That means 71 men would have to take the drug for seven years to prevent one case, Kramer said.<br />
 Another drug in the same family, called dutasteride or Avodart, is thought to be even more potent and is undergoing clinical trials for prevention. It is also recommended in the guideline.<br />
 The medical groups did not issue new recommendations after the completion of the 2003 trial because it appeared that finasteride might have been promoting the growth of more aggressive tumors at the expense of those that are more benign.<br />
 &#8220;Now we know this is not the case,&#8221; Jacoub said. Subsequent studies have shown that shrinkage of the prostate caused by finasteride simply made the aggressive tumors more easily discovered.<br />
 The drug does have side effects in some men, however, including reduced potency and loss of sexual desire. Those effects can go away after a couple of months.  On the other hand, the drug can result in reduced incontinence and fewer urinary problems.<br />
 Cost can also be a problem. The pills cost $2 to $3 a day, or about $1,000 per year, and most insurers do not cover them for cancer prevention.<br />
 Speaking at the news conference, panel member Dr. Howard Sandler of Cedars-Sinai Medical Center said, &#8220;If I tried the medication for a month or two and I got some side effects, then for me personally the benefit wouldn&#8217;t be worth the risk.&#8221; But if there were no side effects, he added, &#8220;I might sleep better at night.&#8221;</p>
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		<title>Michael Phelps faces no charges in South Carolina drug investigation</title>
		<link>http://www.raganvirtualworkshops.com/19868.php4</link>
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		<pubDate>Sun, 15 Feb 2009 20:11:03 +0000</pubDate>
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		<description><![CDATA[
apparently had his picture taken with a marijuana bong in hand just announced that he does not have enough evidence to prosecute the Olympian or anyone else who was present at the November party.
 Richland County (S.C.) Sheriff
 Leon Lott,
 in a news release sent to reporters via e-mail, states that: &#8220;Having thoroughly investigated this [...]]]></description>
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<p>apparently had his picture taken with a marijuana bong in hand just announced that he does not have enough evidence to prosecute the Olympian or anyone else who was present at the November party.<br />
 Richland County (S.C.) Sheriff<br />
 Leon Lott,<br />
 in a news release sent to reporters via e-mail, states that: &#8220;Having thoroughly investigated this matter, we do not believe we have enough evidence to prosecute anyone that was present at the November party.<br />
<span id="more-19868"></span> &#8220;Michael Phelps and I agree that something positive needs to come from this incident and that is a message of not using drugs.&#8221;<br />
 I had nothing to do with Michael Phelps coming to Columbia and making a bad decision. He did that. His bad decision and the highly published photo placed me and the Richland County Sheriff&#8217;s Department in a no win situation. Ignore it and be criticized or address it and be criticized. I chose to do what was right. While to some it may not have been the most popular decision, it was and is the right decision because of the law and the negative impact it could have on our children in Richland County.<br />
 Michael Phelps is truly an American sports hero. I, along with the rest of America, cheered his victories and felt pride when he stood on the podium to receive his medals.<br />
 Even with his star status he is still obligated to obey the laws of our state. He is not immune from his responsibilities to do what is right. He is also human and can make a mistake.<br />
 I took an obligation in my oath as Sheriff to enforce the law equally and fairly without any personal bias or prejudice.<br />
 With Michael Phelps I had to remove his medals, his hero status, and look at him as any other person.<br />
 I felt it was important that he be treated fairly, equally and that a message be conveyed that illegal drug use is illegal by anyone.<br />
 Our investigation focused on the possession, use and distribution of illegal drugs in Richland County. The incident in November only initiated our investigation, which resulted in the arrests of adults who were at the time of their arrests in possession of illegal drugs. Contrary to some, this was not a special investigation or one that impacted our resources on other crimes. This was in fact a short investigation and simple investigation conducted by narcotics investigators whose sole responsibility is to investigate drug violations. The time and resources were quite minimal when compared to other drug investigations. In the time this investigation was being conducted we solved a murder, ATM robberies and numerous other crimes.<br />
 The house of the November party had previously been the subject of a drug case and other crimes. The related house in Irmo had also been the subject of a previous drug case. Both locations were the source of problems in our community.<br />
 The charges of those arrested in this investigation will be handled as we do in other similar type arrests.<br />
 As with any cop, my responsibility is to enforce the law, not to create it or ignore it. Marijuana in the state of South Carolina is illegal and I am obligated to enforce the law again equally, fairly and without personal bias. I would have been remiss in my duty as Sheriff if I would have ignored the November incident and subsequent drug violations we discovered during our investigation.<br />
 By ignoring the November incident, I would have been sending a message of tolerance and condoning the use of illegal drugs. I could not do that, nor have I ever done that. I would be a hypocrite in view of our extensive Drug Abuse Resistance Education (DARE) program that I have been active in for many years. How can we teach kids through DARE not to do drugs, and then look the other way if it is an important person?<br />
 Our message has to be loud, clear, and consistent, don&#8217;t do drugs.<br />
 I have always advocated that we cannot arrest our way out of the drug problem. We must do it through enforcement and education such as the DARE program utilizes.<br />
 Having thoroughly investigated this matter, we do not believe we have enough evidence to prosecute anyone that was present at the November party.<br />
 Michael Phelps and I agree that something positive needs to come from this incident and that is a message of not using drugs.<br />
 He can speak on this issue from his perspective.<br />
 My perspective is that the law pertains to everyone and our drug laws are to be enforced.<br />
 My hope again is that we all take this incident and make something positive from it. Parents please take this opportunity to talk with your children about illegal drug use. During my 34 years in law enforcement I have seen lives and communities destroyed due to drugs. We all must work together to protect our children and our communities. Now is the time to educate our young people, the decisions they make today can impact them for the rest of their lives.&#8221;<br />
 Photo: Michael Phelps is shown during the Beijing Games last August. Credit: Timothy Clary / AFP / Getty Images</p>
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		<title>Cordex files amended SPA for tachycardia drug to FDA</title>
		<link>http://www.raganvirtualworkshops.com/20247.php4</link>
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		<pubDate>Sun, 01 Feb 2009 10:07:54 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Amended]]></category>
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		<description><![CDATA[Feb 19, 2009 (Datamonitor via COMTEX) &#8211;
 &#8212; Cordex Pharma, a developer of new cardiovascular medicines, has submitted to the FDA an amended Phase III protocol for ATPace to be reviewed as a special protocol assessment.
 According to Cordex, the amendment addresses written comments recently received from the FDA in response to the company&#8217;s initial [...]]]></description>
			<content:encoded><![CDATA[<p>Feb 19, 2009 (Datamonitor via COMTEX) &#8211;<br />
 &#8212; Cordex Pharma, a developer of new cardiovascular medicines, has submitted to the FDA an amended Phase III protocol for ATPace to be reviewed as a special protocol assessment.<br />
 According to Cordex, the amendment addresses written comments recently received from the FDA in response to the company&#8217;s initial special protocol assessment (SPA) submission to the FDA in November 2008.<br />
 Amir Pelleg, Cordex&#8217;s<span id="more-20247"></span> president and chief scientific officer, said: &#8220;We are very pleased with the FDA&#8217;s timely response to our initial ATPace SPA submission. We now believe that the written correspondence from the FDA, which clearly outlines all study-design requirements and clinical endpoints, would enable us to generate the efficacy and safety data required for the marketing approval of ATPace.<br />
 &#8220;We look forward to initiating the pivotal Phase III clinical trial for ATPace in paroxysmal supraventricular tachycardia patients.&#8221;</p>
<p>http://www.datamonitor.com</p>
<p> Republication or redistribution, including by framing or similar means,<br />
is expressly prohibited without prior written consent. Datamonitor shall<br />
not be liable for errors or delays in the content, or for any actions<br />
taken in reliance thereon</p>
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		<title>Spectrum says FDA extends review date of cancer drug</title>
		<link>http://www.raganvirtualworkshops.com/20768.php4</link>
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		<pubDate>Fri, 30 Jan 2009 00:34:45 +0000</pubDate>
		<dc:creator>admin</dc:creator>
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		<description><![CDATA[SPPI.O
 ) said
U.S. regulators have extended the review date of its
experimental cancer drug, Zevalin, to July 2.
 The decision by the U.S. Food and Drug Administration comes
after the regulator received a major amendment to the
Supplemental Biologics License Application for use of Zevalin
as a treatment for patients with indolent B-cell non-Hodgkin&#8217;s
lymphoma (NHL), the company said.
 The [...]]]></description>
			<content:encoded><![CDATA[<p>SPPI.O<br />
 ) said<br />
U.S. regulators have extended the review date of its<br />
experimental cancer drug, Zevalin, to July 2.<br />
 The decision by the U.S. Food and Drug Administration comes<br />
after the regulator received a major amendment to the<br />
Supplemental Biologics License Application for use of Zevalin<br />
as a treatment for patients with indolent B-cell non-Hodgkin&#8217;s<br />
lymphoma (NHL), the company said.<br />
 The drug has received priority review status from the FDA.<br />
<span id="more-20768"></span> An estimated 30,000 people in the United States will be<br />
diagnosed this year with indolent NHL, a slow-growing cancer of<br />
the lymphatic system, according to the National Cancer<br />
Institute.<br />
 The company also said it would acquire the 50 percent<br />
interest it does not already own in RIT Oncology LLC, a joint<br />
venture between the company and Cell Therapeutics Inc (<br />
 CTIC.O<br />
 )<br />
to develop Zevalin, for $18 million.<br />
 Sales of Spectrum&#8217;s Fusilev, a drug approved to treat<br />
osteosarcoma, a type of bone cancer, will help fund the<br />
acquisition, Chief Executive Rajesh Shrotriya said.<br />
 Shares of Irvine, California-based Spectrum closed at $1.65<br />
Friday on Nasdaq, while Cell Therapeutic shares closed at 5<br />
cents.<br />
 (Reporting by Anand Basu in Bangalore; Editing by Pratish<br />
Narayanan)</p>
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		<title>FDA: &#039;Mistake&#039; Not To Include Doctor At Eli Lilly Drug Panel</title>
		<link>http://www.raganvirtualworkshops.com/20853.php4</link>
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		<pubDate>Thu, 29 Jan 2009 15:42:19 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[News]]></category>
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		<description><![CDATA[-(Dow Jones)- U.S. federal regulators on Monday acknowledged it was
a mistake to &#8220;dis-invite&#8221; a leading cardiologist to a panel that was deciding
whether to recommend approval for a controversial anti-clotting drug made by
 Eli
Lilly &#038; Co.
 (LLY).
 Dr. Sanjay Kaul, a cardiologist at Cedars-Sinai Heart Institute in
 , was scheduled to participate in a
 Feb. 3
 [...]]]></description>
			<content:encoded><![CDATA[<p>-(Dow Jones)- U.S. federal regulators on Monday acknowledged it was<br />
a mistake to &#8220;dis-invite&#8221; a leading cardiologist to a panel that was deciding<br />
whether to recommend approval for a controversial anti-clotting drug made by<br />
 Eli<br />
Lilly &#038; Co.<br />
 (LLY).<br />
 Dr. Sanjay Kaul, a cardiologist at Cedars-Sinai Heart Institute in<br />
 , was scheduled to participate in a<br />
 Feb. 3<br />
 Prasugrel, an anti-clotting drug that has been linked<br />
to dangerous internal bleeding.<br />
<span id="more-20853"></span> Panel members at the meeting voted 9 to 0 to recommend approval of the drug.<br />
 Several days before the meeting, FDA managers received a call from<br />
 saying it had questions about Kaul&#8217;s inclusion in the meeting because he had<br />
authored several papers that were critical of Prasugrel, FDA officials said.<br />
 representatives weren&#8217;t immediately available to comment. This news was<br />
first reported by the blog HeartWire.<br />
 Under federal regulation, the FDA can exclude members from participating in a<br />
meeting if they have a financial conflict of interest, such as having received<br />
consulting fees from a company, or for &#8220;intellectual bias.&#8221; Determining<br />
intellectual bias, or whether someone has already made their mind up about<br />
whether a drug should be on the market, is difficult, and FDA officials say a<br />
series of errors lead to Kaul&#8217;s exclusion from the meeting.<br />
 FDA managers that screen panel members only asked Kaul about his financial<br />
conflicts of interest, of which he had none, not about any intellectual bias,<br />
said Dr.<br />
 , director of the FDA&#8217;s drug division.<br />
 for the<br />
meeting.<br />
 &#8220;At every step of the way there were errors by multiple parties,&#8221; Woodcock<br />
said.<br />
 The FDA hasn&#8217;t done a formal review to determine whether Kaul was actually<br />
intellectually biased, but one FDA official said he would have welcomed the<br />
cardiologist&#8217;s input at the meeting.<br />
 &#8220;In my own personal opinion I didn&#8217;t see anything in [Kaul's] writings&#8230;that<br />
would preclude him from serving on the committee,&#8221; said<br />
 , FDA&#8217;s<br />
director of the Office of New Drugs. &#8220;I think he would have been a very valuable<br />
member.&#8221;<br />
 To be sure, FDA officials described the discussion at the meeting as robust<br />
and don&#8217;t think the kerfuffle invalidates the results of the panel.<br />
 Prasugrel isn&#8217;t on the market yet, and it&#8217;s unclear when the FDA will make a<br />
decision about whether to approve it. The drug, co-marketed by<br />
 Daiichi Sankyo Co.<br />
 (4568.TO), is expected to bring in ample sales for<br />
the companies.<br />
 -By Jared A. Favole, Dow Jones Newswires; 202-862-9207; jared.favole@<br />
dowjones.com<br />
 (END) Dow Jones Newswires<br />
  02-23-09 1807ET<br />
  Copyright (c) 2009 Dow Jones &#038; Company, Inc.</p>
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		<title>FDA nod key to drug cos&#039; US growth</title>
		<link>http://www.raganvirtualworkshops.com/19653.php4</link>
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		<pubDate>Fri, 16 Jan 2009 17:03:55 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Health]]></category>
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		<category><![CDATA[growth]]></category>

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		<description><![CDATA[Ranbaxy, Dr Reddy&#8217;s and other Indian drug makers, which earn a third of their earnings from selling products in the US, need higher drug approvals from the Food and Drug Administration (FDA) of that country in the next financial year to maintain 20 per cent sales growth.
 The requirement comes at a time when the [...]]]></description>
			<content:encoded><![CDATA[<p>Ranbaxy, Dr Reddy&rsquo;s and other Indian drug makers, which earn a third of their earnings from selling products in the US, need higher drug approvals from the Food and Drug Administration (FDA) of that country in the next financial year to maintain 20 per cent sales growth.<br />
 The requirement comes at a time when the US, the world&rsquo;s biggest drug market, is facing a slowdown and one of India&#8217;s leading drug makers, Ranbaxy, is being investigated<span id="more-19653"></span> by US FDA for violating rules.<br />
 Sun Pharma, Glenmark and Dr Reddy&#8217;s would require at least 12-14 approvals to meet a 20 per cent sales growth target in the US, a recent Credit Suisse report said. Ranbaxy and Lupin, which currently face regulatory issues with the US FDA, might find it tough to achieve this target, the report said.<br />
 The US market accounts for 20-30 per cent of revenues for major Indian pharmaceutical companies.<br />
 In the last three years, major Indian drug companies grew at over 20 per cent in the US market and in the nine months of 2008-09 posted an average growth of 22 per cent. IMS Health estimates that sales of generics will reach $75 billion over the next five-year period, with a compound annual market growth rate of 14-17 per cent.<br />
 According to Dr R B Smarta, Managing Director of Interlink Marketing Consultancy, future prospects for the generic business in the US will depend on judicious product selection with less competition and innovative marketing strategy.<br />
 Normally, the US FDA approves a marketing application for a generic drug a few months before patent expiry of the innovator&#8217;s drug. A first to file applicant can exclusively sell its generic version for six months from the date of expiry, as per the US laws for generic drugs.<br />
 It is estimated that by the end of 2009 over 100 drugs, including 13 big formulations of companies such as GlaxoSmithKline, Pfizer, Novartis and Takeda, will lose patent protection.<br />
 In the year ended 2008, a few high-value drugs went off-patent. These drugs included Merck &#038; Co&#8217;s Fosamax (alendronate), Pfizer&#8217;s Camptosar (irinotecan) and Wyeth&#8217;s Effexor XR (venlafaxine).<br />
 Indian generic companies account for more than 40 per cent of marketing applications in the US. &#8220;Drug companies with a good product pipeline in the US and Europe will not suffer in near or long-term future. Business and future prospects for them will depend on the products they choose,&#8221; said Hitesh Gajaria, Executive Director, KPMG India.</p>
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		<title>Thai FDA okays heart drug</title>
		<link>http://www.raganvirtualworkshops.com/18676.php4</link>
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		<pubDate>Fri, 16 Jan 2009 14:20:33 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Health]]></category>
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		<description><![CDATA[Bangkok &#8211; Thailand&#39;s Food and Drug Administration (FDA) has certified the quality of the Indian-made generic heart drug Clopidogrel which is 23 times cheaper than its patented alternative Plavix, media reports said on Saturday.
 &#8220;We confirm that every lot of Clopidogrel imported from India has been tested, with its quality and efficacy approved by the [...]]]></description>
			<content:encoded><![CDATA[<p>Bangkok &#8211; Thailand&#39;s Food and Drug Administration (FDA) has certified the quality of the Indian-made generic heart drug Clopidogrel which is 23 times cheaper than its patented alternative Plavix, media reports said on Saturday.<br />
 &#8220;We confirm that every lot of Clopidogrel imported from India has been tested, with its quality and efficacy approved by the Department of Medical Science before being distributed to hospitals,&#8221; FDA deputy secretary Veerawan<span id="more-18676"></span> Tangkaew said in an interview with The Nation newspaper.<br />
 The certification was deemed necessary after hospitals, pharmaceutical companies and individuals questioned the efficacy of the copycat drug which costs only 0.08 cents per pill compares with $2.03 for its patented rival Plavix.<br />
 Thailand has already imported 6 million Clopidogrel pills from India under its Compulsory Licensing scheme, that allows the government to import generic pharmaceuticals to treat major diseases prevalent in the country.<br />
 The generic pharmaceuticals are only used for patients under the Universal Health Scheme and the Social Security Fund, both of which are heavily subsidized by the government. In theory, private hospitals and their patients must use patented pharmaceuticals.<br />
 Thailand&#39;s use of Compulsory Licensing, a tactic which is recognized by the World Trade Organization (WTO), has been highly controversial, pitting several multinational pharmaceutical giants against the kingdom. &#8211; Sapa-dpa</p>
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		<title>Drug clinic&#039;s files Special Report Drug clinic&#039;s files</title>
		<link>http://www.raganvirtualworkshops.com/19610.php4</link>
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		<pubDate>Sun, 11 Jan 2009 11:22:10 +0000</pubDate>
		<dc:creator>admin</dc:creator>
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		<description><![CDATA[
In Orlando, a 38-year-old contractor suffers from erectile dysfunction, a side effect of the drug he takes for depression. The anti-ED prescription his doctor gave him doesn&#8217;t help. He seeks steroids instead.
 And in a town north of Seattle, an eighth-grade boy wants steroids for school sports. If he can get his weight up to [...]]]></description>
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<p>In Orlando, a 38-year-old contractor suffers from erectile dysfunction, a side effect of the drug he takes for depression. The anti-ED prescription his doctor gave him doesn&#8217;t help. He seeks steroids instead.<br />
 And in a town north of Seattle, an eighth-grade boy wants steroids for school sports. If he can get his weight up to 170, he thinks he can make the football team.<br />
 Here, from the business records of a Florida wellness center that was closed<span id="more-19610"></span> after a 2007 law enforcement raid, are the faces of the nation&#8217;s infatuation with performance-enhancing drugs &#8211; people who sought to buy steroids, human growth hormone and other powerful prescription drugs over the Internet to address deeply felt problems and concerns.<br />
 Since the BALCO steroid scandal broke in 2003, the national dialogue about performance-enhancing drugs has focused on high-profile athletes accused of using steroids to gain an unfair advantage in the hyper-competitive world of elite sports. Last week, New York Yankees superstar Alex Rodriguez went on national television to confess that he had used banned drugs, as Sports Illustrated first reported; two days later, former American League Most Valuable Player Miguel Tejada pleaded guilty to lying to Congress about a teammate&#8217;s steroid use while with the Oakland Athletics. That focus on celebrity athletes and banned drugs is likely to intensify March 2, when former Giants slugger Barry Bonds, baseball&#8217;s all-time leading home run hitter, is scheduled to go on trial in San Francisco, accused of lying under oath when he testified he had never knowingly used steroids.<br />
 But computerized records reviewed by The Chronicle show that only a handful of the thousands of customers of the Palm Beach Rejuvenation Center, as this online clinic was called, were sports stars whose use of banned drugs might bring another multimillion-dollar contract.<br />
 Instead, the clinic&#8217;s customers were ordinary people with an array of medical, physical and emotional complaints &#8211; and faith that their problems would be solved if only they could obtain drugs that their own physicians wouldn&#8217;t prescribe for them.<br />
 &#8220;Is this truly the miracle I have been waiting on?&#8221; a Tennessee man e-mailed to the clinic in 2005. &#8220;And how long will it take to see results? And how much will it cost?&#8221;<br />
 The Palm Beach Rejuvenation Center was part of a network of online clinics and pharmacies in the southeastern United States that was targeted by the Albany, N.Y., district attorney for illegal sale of steroids and growth hormone. By law, the drugs can only be prescribed for valid medical use.<br />
 Often, the district attorney charged, physicians hired by the center wrote fake prescriptions to make Internet drug sales seem legitimate. Many prescriptions for growth hormone were written by a former dentist who had lost his license for fraud and incompetence, Florida state records show.<br />
 After the center was raided in 2007, the clinic&#8217;s top two executives and a physician who worked there pleaded guilty to drug-related felonies, according to a spokesman for the Albany district attorney&#8217;s office. They were among 14 people convicted of crimes in the prosecution of the network of pharmacies and clinics. Further prosecutions stalled in 2008 after an Albany judge dismissed charges against proprietors of an online pharmacy in Orlando that also was targeted, citing missteps by prosecutors. Today, the Palm Beach Rejuvenation Center is out of business.<br />
 For an inquiry into the who and why of the nation&#8217;s demand for steroids, The Chronicle reviewed six years of transactions and 66,000 customer records from the Palm Beach Rejuvenation Center, focusing especially on a sample of about 2,200 people whose contact with the clinic included detailed information about why they sought the drugs.<br />
 The Chronicle has withheld customers&#8217; names out of privacy concerns.<br />
 Queries came from prospective customers in all 50 states and more than 30 foreign countries. Customers ranged widely in age, occupation and physical condition. There were soldiers fighting in Iraq and elementary school teachers in Middle America; police officers and firefighters; Hollywood stuntmen; pastors and physicians; retirees and schoolchildren. Two inquiries came from officials of the United Nations. One came from a lawyer for the U.S. Congress.<br />
 Obesity and sex problems were by far the most common reasons that customers cited for seeking the drugs.<br />
 Other people said they wanted drugs to improve at amateur sports; to recover from injury or illness; or to slow the aging process or otherwise improve how they looked. Although steroid abuse is associated with heart and liver damage, prostate cancer, depression and birth defects, few customers expressed misgivings about side effects or questioned the legality of obtaining prescription drugs online.<br />
 Experts who reviewed The Chronicle&#8217;s findings said the quest for performance-enhancing drugs reflects a modern &#8220;instant gratification culture&#8221; and a related urge for &#8220;magic fixes&#8221; to health problems, as Charles Yesalis, professor emeritus at Pennsylvania State University and a consultant on sports doping issues, put it.<br />
 Dr. Gary Wadler, a New York University medical professor and an official with the Olympic movement&#8217;s World Anti-Doping Agency, described the dynamic this way: &#8220;You aren&#8217;t happy with your body, you go get a drug and that can change it &#8211; obviously, things like exercise and nutrition are too slow,&#8221; he said.<br />
 Unfortunately, Wadler said, people run grave risks when they take powerful drugs without medical supervision &#8211; or, indeed, without medical need.<br />
 &#8220;I talk myself blue in the face, trying to explain to people that this behavior may be hurtful,&#8221; he says. &#8220;They say, &#8216;Oh come on, I take 15 pills a day and I&#8217;m doing great.&#8217; &#8221;<br />
 According to the records, customers heard about the center from magazine advertising, other steroid users, and, especially, from surfing the Web. Not every inquiry resulted in a sale.<br />
 But some customers spent thousands, encouraged by a sales staff that pushed steroids and growth hormone, as well as other prescription drugs to offset the side effects of steroid use.<br />
 In six years, the clinic filled $38 million worth of orders, the records show. Here, from the records, is a look at the ordinary people who made up the steroid clinic&#8217;s clientele.<br />
 No. 1: Obesity<br />
 Steroids &#8211; artificial testosterone &#8211; were developed to treat muscle wasting, while human growth hormone is prescribed for dwarfism in children. But as competitive bodybuilders long have known, the drugs also help the body burn fat, replacing it with lean muscle. Of the people whose records reflect their reason for seeking performance-enhancing drugs, 26 percent said they hoped to lose weight. Some said they were desperate to lose hundreds of pounds.<br />
 &#8220;I&#8217;ve tried all kinds of diets and they just don&#8217;t work for me,&#8221; wrote a 41-year-old man in Maitland, Fla. &#8220;I just weighed myself this past weekend. I&#8217;m up to 432 lbs.&#8221;<br />
 Men in Tallahassee and Long Beach had the same goal: &#8220;Lose 200 pounds,&#8221; they both wrote.<br />
 In the eastern Massachusetts town of Rochester, a 34-year-old man needed to shed 100 pounds.<br />
 &#8220;I work out hard four hours a day and results are very small,&#8221; he wrote.<br />
 &#8220;Can you please help me out with some testosterone? &#8230; I don&#8217;t want to die from over weight.&#8221;<br />
 Among them, too, was the Berkeley seminarian, who blamed her weight problems in part on a thyroid condition. &#8220;I currently weigh 310 pounds, and am considering this therapy as an adjunct to weight loss,&#8221; she wrote, saying she wanted growth hormone. She gave a detailed medical history, then broke off contact without making a purchase.<br />
 For some people intent on losing weight, the lure of steroids and growth hormone was a family affair.<br />
 &#8220;Me and my 14 yr old son and 16 yr old daughter want to join this,&#8221; wrote a woman in the central Iowa town of Newton. &#8220;My son weighs 280 at 14. Plz help him, mainly. I had the gastric bypass and lost my weight.&#8221;<br />
 Some said they had used steroids to control their weight in the past.<br />
 &#8220;In 1994, (I) lost close to 75 lbs in a very short time &#8211; three shots a week and a strict diet,&#8221; wrote a woman in Phoenix. &#8220;Gained some weight back, need to lose this.&#8221;<br />
 A handful of prospective customers weren&#8217;t obese at all. A Detroit-area man who said his percentage of body fat was 13 percent &#8211; far leaner than average, according to experts &#8211; wanted drugs to lose even more weight.<br />
 &#8220;Trying to get my body fat composition down to 9-10%,&#8221; he wrote.<br />
 &#8220;Currently train 3 days a week with a personal trainer with 3 additional days of cardio and weight training.&#8221;<br />
 A sense of urgency was reflected in some queries.<br />
 &#8220;I am 30 yrs of age and putting on weight really fast,&#8221; wrote a New Jersey man seeking growth hormone. &#8220;I am getting married next June and I want to burn off some of the fat ASAP! Can you help me out?&#8221;<br />
 As a man in Grand Rapids, Mich., put it: &#8220;I WANT IT OFF. I WANT TO BE A LEAN STUD AGAIN, INSTEAD OF A FATTY!!!&#8221;<br />
 No. 2: Sex problems<br />
 Steroid abuse has been linked to sexual dysfunction in men. Nevertheless, sex problems &#8211; especially erectile dysfunction and impaired libido &#8211; were the second most common complaint cited by people who sought steroids, 17 percent of the total. Many believed more testosterone would solve the problem.<br />
 &#8220;For sex I have (to) eat a bottle of Cialis, which doesn&#8217;t seem to work half the time,&#8221; wrote a man in Boonville, Ind., referring to the heavily advertised ED drug. &#8220;My doctor says I&#8217;m fine, go figure.&#8221; He sought testosterone supplements.<br />
 &#8220;My mind says yes but my body says no,&#8221; wrote a 71-year-old man in Bedford Heights, Ohio. He sought steroids that wouldn&#8217;t react adversely with his diabetes and hypertension medication.<br />
 At times, a mate&#8217;s dissatisfaction led to the quest for steroids. A man living in Austria wrote that he was on the verge of divorce because of an unhappy love life.<br />
 &#8220;I have to try something secretly that I can surprise her with,&#8221; he wrote. Occasionally the query came directly from the dissatisfied mate.<br />
 &#8220;Will it help my husband&#8217;s sex drive?&#8221; e-mailed a woman who didn&#8217;t provide the clinic with her home address. &#8220;Because he drinks a lot of beer and I think it interferes.&#8221;<br />
 Many customers had decided that their bodies weren&#8217;t producing a normal amount of testosterone.<br />
 &#8220;I don&#8217;t have a deep voice,&#8221; wrote a 23-year-old New Jersey man. &#8220;I have a very low sexual drive, and I&#8217;m very sensitive with no aggressiveness at all.&#8221;<br />
 Some sought steroids to counteract the effects of prescribed medicines.<br />
 A Minneapolis woman with &#8220;no sex drive&#8221; blamed the antidepressant drug Effexor; a man in Nashville blamed either his Prozac anti-anxiety medication or the Lotrel he took for high blood pressure. Other queries came from diabetics who blamed their dysfunction on insulin.<br />
 &#8220;As a man I feel lost,&#8221; wrote a diabetic man from Glen Burnie, Md.<br />
 Among them, too, was the Orlando contractor who blamed ED on his antidepressant meds. Over a three-month period in 2005, he bought $1,000 worth of human growth hormone and the injectable steroid Sustanon, along with syringes.<br />
 Some sought steroids for issues of sexual identity.<br />
 &#8220;My voice sounds like a female, I want to change it,&#8221; wrote a Middletown, N.J., man.<br />
 &#8220;I&#8217;m a transgender woman, not wanting to completely morph into a male,&#8221; wrote a woman in Brooklyn. She sought steroids for &#8220;body fat redeposit, less moodiness, less sensitivity, etc.&#8221;<br />
 In some cases, customers blamed steroids for their sexual dysfunction, according to the e-mails. A repeat customer from Dixon, Mo., complained of &#8220;no sex drive&#8221; and &#8220;nipple sensitivity&#8221; while cocktailing the bodybuilders&#8217; steroids Winstrol and Deca-durabolin. Both are common side effects of steroid abuse.<br />
 &#8220;Get him on growth!&#8221; wrote the clinic sales clerk in a note on the account, suggesting the patient be sold human growth hormone instead of steroids. For the nipple problem, the clerk proposed the female anti-cancer drug anastrozole, sometimes used by male steroid users to counteract the development of female sexual characteristics.<br />
 Some were willing to run profound risks to overcome sexual problems. A Michigan man who suffered impotence after prostate surgery wanted steroids despite an explicit warning from his physician.<br />
 &#8220;Urologist seems to feel that testosterone is worst thing to take at this time as (the) grade of cancer I had seems to &#8216;feed&#8217; off testosterone,&#8221; he wrote. Nevertheless, he said he felt it was safe to begin using steroids &#8211; he&#8217;d been cancer-free for 14 months.<br />
 No. 3: Sports<br />
 Athletes &#8211; most of them amateurs seeking an edge in sports they played for fun &#8211; made up 13 percent of the people who described why they sought steroids.<br />
 As The Chronicle reported in 2007, a handful of the clinic&#8217;s customers were major-league baseball players. They included pitcher Paul Byrd, who bought $25,000 worth of HGH while on the Atlanta Braves and two other teams, and outfielder Jose Guillen, who ordered growth hormone and steroids while playing for the Cincinnati Reds and Oakland Athletics. Another customer was former Giants star Matt Williams, who ordered growth hormone after he retired from the game.<br />
 But far more of the inquiries and orders came from amateur athletes &#8211; runners, cyclists, tennis players and, especially, bodybuilders.<br />
 &#8220;Just interested in getting huge in a short time,&#8221; wrote a man in suburban Chicago.<br />
 &#8220;Will it be able to turn me into a Greek god of muscle?&#8221; asked a 265-pound weightlifter from Nashville.<br />
 A New Mexico man who said he had already run seven marathons sought drugs so he could compete in an Ironman Triathlon.<br />
 &#8220;Forever young,&#8221; he wrote.<br />
 Athletes on the fringe of elite sports inquired.<br />
 A professional arm wrestler from Beebe, Ark., bought $1,200 worth of the steroids nandrolone and stanozolol in 2004 and 2005, records show.<br />
 Another inquiry came from a quarterback for the Soquel-Capitola Sharks of the Northern California Amateur Football Federation. &#8220;I will be taking injectable HGH,&#8221; he wrote. &#8220;I want to increase strength but I don&#8217;t care about getting too big. &#8230; I don&#8217;t want to grow breasts, either.&#8221; He didn&#8217;t make a purchase.<br />
 Some customers had Olympic dreams.<br />
 One was a former collegiate runner who has repeatedly tried to make the Olympic sprint team, most recently last year, at age 37. In 2001, he was banned from sports for two years after testing positive for steroids, records show. He ordered about $300 worth of growth hormone from the clinic in 2004, the year he was reinstated. &#8220;I want to be the world&#8217;s fastest human,&#8221; he wrote on his Web site.<br />
 A 46-year-old competitive cyclist from Santa Monica wrote that she was considering the Olympic trials because the ban on transsexual competitors had been lifted.<br />
 &#8220;I&#8217;m interested in HGH to help me compete,&#8221; wrote the woman. &#8220;I was born XXY chromosomally and (am) not your typical&#8221; transsexual.<br />
 A basketball referee in Pea Ridge, Ark., bought $2,300 worth of steroids. A football coach in Indiana inquired about growth hormone &#8211; one of 14 inquiries from people whose e-mail addresses indicated they were involved in coaching.<br />
 Then there was the query from the schoolboy in Snohomish, north of Seattle.<br />
 &#8220;I want to weigh 170 for football and wrestling next year,&#8221; he wrote. &#8220;And I want to be a lot stronger and faster.&#8221;<br />
 The note indicated the boy was 14. He was among about 150 prospects rebuffed because they were too young, the records show.<br />
 No. 4: Total rejuvenation<br />
 For some, steroids held out the prospect of recovering from serious injury or illness. For others, the quest for drugs was simply about looking better or younger.<br />
 People who said they had suffered serious injury or illness made up about 11 percent of the queries that specified why steroids were being sought.<br />
 &#8220;I was in the best shape of my life until about a year ago when a drunk driver hit me,&#8221; wrote an Akron, Ohio, man. A severe back injury left him unable to exercise. &#8220;Since the accident I&#8217;ve lost a good 15-20 pounds of muscle mass and gained at least 20 pounds of body fat,&#8221; he wrote. &#8220;While (I have) never tried enhancement products before I am in desperate need of help getting my life back.&#8221;<br />
 An Arizona woman also had an urgent concern &#8211; her 49-year-old husband&#8217;s chronic pain from tendinitis in shoulders and knees. But there was an additional concern &#8211; he suffered from &#8220;stage 4 primary bi-lateral cirrhosis of the liver,&#8221; as she put it. Would steroids further harm his liver?<br />
 Other queries came from women &#8220;in desperate need&#8221; of relief from menopause, as a Lehigh Acres, Fla., e-mailer put it.<br />
 &#8220;I am going through menopausal hell and all the doctors want to do is put me on antidepressants,&#8221; e-mailed a woman in Pasadena. &#8220;There has got to be another way!&#8221;<br />
 But more than 10 percent of the queries came from people who acknowledged they had no medical problem at all.<br />
 &#8220;Basically, I want to look good naked,&#8221; a Daly City man wrote.<br />
 &#8220;I would like to look good in my leather thong and chaps,&#8221; a Tacoma man wrote.<br />
 A self-described New York metrosexual wondered whether steroids would help him &#8220;maintain a younger fresher look to my face,&#8221; while a New Jersey man sought drugs to make him taller: &#8220;I am just too short for a professional look.&#8221;<br />
 &#8220;I would love to have my slim figure again after having a baby one year ago,&#8221; a Los Angeles woman wrote.<br />
 Others wanted growth hormone for its reputed anti-aging properties.<br />
 &#8220;I tried my normal physician and she blew me off by just saying &#8216;you&#8217;re getting older,&#8217; &#8221; wrote a Raleigh, N.C., man with a heart condition. &#8220;Needless to say this was not the answer I was looking for.&#8221; He bought about $2,800 worth of growth hormone and steroids, the records show.<br />
 A 92-year-old woman from La Brea (Orange County) volunteered to &#8220;be in a research program to see how long &#8216;I can be around,&#8217; &#8221; as she put it.<br />
 Other queries defied categorizing. A Southern California woman sought growth hormone to cure her son&#8217;s thinning hair. &#8220;His wife is against this,&#8221; she wrote. &#8220;She thinks the product is harmful.&#8221;<br />
 An Orange County business consultant with a new baby sought growth hormone &#8220;to increase breast milk supply,&#8221; she wrote. An Indiana farmer inquired about growth hormone for his &#8220;show animals (goats and sheep),&#8221; while a Denver man also sought growth hormone for his pet dog, which was &#8220;not growing tall enough,&#8221; he wrote.<br />
 A Louisiana man inquired about steroids to counter the effects of youthful steroid use. &#8220;During my college years of ball playing test(osterone) was used by all of the players,&#8221; he wrote. &#8220;And now years later I am experiencing side affects like sexual issues and joint problems.&#8221;<br />
 For clients, the clinic drew heavily on local people &#8211; 11 percent of the customers were from Florida. But nearly as many came from California (10 percent), and queries came from prospective customers in every state, and from around the world &#8211; South Africa, Bangladesh, Hong Kong, American Samoa.<br />
 Most customers didn&#8217;t describe their occupations. Those whose occupations could be identified ranged widely.<br />
 Ninety-one queries came from U.S. armed forces personnel, 21 of whom said they had been deployed to the Iraq war.<br />
 &#8220;U.S. Army soldier stationed in Iraq,&#8221; wrote a sergeant from Virginia. &#8220;I&#8217;m very active in sports and physical training. Local (physician&#8217;s assistant) recommended testos(terone) therapy.&#8221;<br />
 A soldier from Iowa wrote: &#8220;I want to build muscle pretty quick but do it in a healthy way. I am 19 years old and I have tried all kind of things ever since I have been here in Iraq.&#8221;<br />
 From Washington state, another soldier wrote: &#8220;While on military duty in Iraq we used test(osterone). Test(osterone) enhanced my physical abilities in the field, and noticed a feeling of well being &#8230; How do we go about this?&#8221;<br />
 Queries also came from police officers, deputy sheriffs and firefighters &#8211; although some were reluctant to acknowledge their ties to law enforcement.<br />
 In 2005, an Alabama man who said he worked in a bank inquired about nandrolone decanoate, a bodybuilders&#8217; steroid.<br />
 &#8220;Very cautious,&#8221; the clerk wrote in a note on the file, and then later noted why. &#8220;He is actually a police officer.&#8221;<br />
 A customer from Biloxi, Miss., was described as a &#8220;28 year old cop &#8230; big-time loss of libido.&#8221;<br />
 Educators &#8211; from grade schools to colleges &#8211; also expressed interest. A third-grade teacher from Orlando sought steroids &#8220;for health, more sex appeal and to help slow down Mother Nature&#8217;s aging,&#8221; as she put it. Another Florida teacher had progesterone shipped to her elementary school in Boca Raton. An associate professor of psychology at the University of Southern California and a clinical instructor at the UCLA medical school inquired, as did a professor of food science at the University of Florida.<br />
 In all, the clinic got queries from more than 400 people using e-mail addresses from the nation&#8217;s colleges and universities, including Harvard, Yale, Princeton and UC Berkeley. Most were probably students.<br />
 More than 80 queries came from government employees from agencies including the Department of Veterans Affairs, the Federal Bureau of Prisons, NASA, the Department of Homeland Security and the Department of Justice.<br />
 Inquiries also came from U.N. officials, one in Amsterdam, the other in Jerusalem. &#8220;I am taking Sytropin HGH spray presently,&#8221; he wrote, referring to an ersatz growth hormone product sold on the Internet. &#8220;Can I take your product at the same time?&#8221;<br />
 An order also came from an attorney in the U.S. House of Representatives&#8217; Office of the Legislative Counsel, which helps lawmakers draft bills.<br />
 In 2006, using her government e-mail account, she ordered $346 worth of growth hormone and testosterone. The records don&#8217;t reflect why she wanted the products.<br />
 About 9 percent of the queries came from prospective customers who wanted to know about potential side effects.<br />
 They included a Hollywood stuntman with a seizure disorder who wondered whether HGH would react adversely with his anti-convulsant medication.<br />
 By contrast, fewer than 1 percent were worried about legal consequences of using the drugs.<br />
 Among them was a Texas oil refinery firefighter who said he was subject to drug testing: Would steroids also trigger a positive test?<br />
 Meanwhile, some customers contacted the clinic to blame new physical problems on their use of the powerful drugs.<br />
 A pastor in Crystal River, Fla., complained of rapid heartbeat and flushed skin after using growth hormone and injectable testosterone. The clinic switched him to a testosterone cream.<br />
 After cycling through $1,800 worth of steroids and HGH, a 35-year-old New Jersey man reported he had been hospitalized with high blood pressure and elevated heart rate. He was ceasing steroid use, he said.<br />
 A Petaluma woman, meanwhile, contended that steroids had driven her husband into depression.<br />
 &#8220;He can no longer take nandrolone decanoate because it causes a change in his personality,&#8221; a clerk wrote in the file. &#8220;His wife is concerned he might do something drastic.&#8221;<br />
 .</p>
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		<title>FL police, drug task force team to seize drugs, arrest 3</title>
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		<pubDate>Tue, 06 Jan 2009 18:45:54 +0000</pubDate>
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		<description><![CDATA[
Three men have been arrested in a Washington County Narcotics Task Force probe in Forest Lake. Authorities also seized 62 pounds of khat, a leafy controlled substance narcotic, during a joint effort with the Forest Lake Police Department.
 The drugs were seized and the arrests were made at 1:40 p.m. on Tuesday at the UPS [...]]]></description>
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<p>Three men have been arrested in a Washington County Narcotics Task Force probe in Forest Lake. Authorities also seized 62 pounds of khat, a leafy controlled substance narcotic, during a joint effort with the Forest Lake Police Department.<br />
 The drugs were seized and the arrests were made at 1:40 p.m. on Tuesday at the UPS Store, 2009 W. Broadway Ave. where officers from the two police agencies converged.<br />
 During the arrest, police recovered 62 pounds<span id="more-20137"></span> of the drug and found additional boxes containing the drug in a rented Ford Explorer the three men were driving. The khat had been packed in 225 bundles making up the 62 pounds, authorities said.<br />
 Chief of Police Clark Quiring said authorities believe the Forest Lake store was being used as a drop point for illegal drugs that are being smuggled into the country.<br />
 Quiring said the drugs recovered in Forest Lake on Tuesday had street value ranging in price from $8000 to nearly $12,000.<br />
 &ldquo;Certainly, this is a pipeline to downtown Minneapolis,&rdquo; Quiring said. &ldquo;They are using our community as a passing zone.&rdquo;<br />
 The three men arrested are all from Minneapolis.<br />
 &bull;Abdimajid Said, 33, of 1819 Elliot Ave. S.<br />
 &bull;Abdikarin M. Suleiman, 26, of 1600 S. 6th St.<br />
 &bull;Jamal M. Ibrahim, 28, of 2500 Blaisdell Ave. S.<br />
 All three were booked in the Washington County Jail, Stillwater, on probable cause of felony fifth-degree possession of a controlled substance.<br />
 Khat is a leafy substance that is grown largely in Eastern Africa. Police said that the leaves are harvested, wrapped in banana leaves and shipped in bundles to the West. In many cases in the past, Quiring said, authorities in the United States have intercepted drugs that were shipped from England.<br />
 The arrests were made without incident and authorities received cooperation from store employees, Quiring said.<br />
 The investigation was carried out by two members of the drug task force who were assisted by four Forest Lake officers, Quiring said.<br />
 Quiring said it is possible that the other boxes of drugs found in the vehicle had been picked up earlier in the day from other stores.</p>
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		<title>Drug recommended to prevent prostate cancer in some older men</title>
		<link>http://www.raganvirtualworkshops.com/21036.php4</link>
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		<pubDate>Tue, 06 Jan 2009 14:06:10 +0000</pubDate>
		<dc:creator>admin</dc:creator>
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		<description><![CDATA[The panel stopped short of recommending that all men take the drug because clinical trials have not yet shown that it reduces deaths.
 Prostate cancer is the second-leading cause of cancer deaths among men, behind lung cancer, with 186,000 new cases diagnosed and 28,660 deaths each year.
 Finasteride is used in low doses under the [...]]]></description>
			<content:encoded><![CDATA[<p>The panel stopped short of recommending that all men take the drug because clinical trials have not yet shown that it reduces deaths.<br />
 Prostate cancer is the second-leading cause of cancer deaths among men, behind lung cancer, with 186,000 new cases diagnosed and 28,660 deaths each year.<br />
 Finasteride is used in low doses under the brand name Propecia as an anti-balding drug and in higher doses under the name Proscar for shrinking enlarged prostate<span id="more-21036"></span> glands. The dose recommended for cancer prevention is the same dosage used in Proscar.<br />
 The drug interferes with the production of male hormones, starving the tumors of fuel they need to grow.<br />
 A major clinical trial reported in 2003 showed that finasteride reduced the risk of prostate cancer by about 25% in men who took it, preventing about 15 cases in every 1,000 men. That means 71 men would have to take the drug for seven years to prevent one case, Kramer said.<br />
 Another drug in the same family, called dutasteride or Avodart, is thought to be even more potent and is undergoing clinical trials for prevention. It is also recommended in the guideline.<br />
 The medical groups did not issue new recommendations after the completion of the 2003 trial because it appeared that finasteride might have been promoting the growth of more aggressive tumors at the expense of those that are more benign.<br />
 &#8220;Now we know this is not the case,&#8221; Jacoub said. Subsequent studies have shown that shrinkage of the prostate caused by finasteride simply made the aggressive tumors more easily discovered.<br />
 The drug does have side effects in some men, however, including reduced potency and loss of sexual desire. Those effects can go away after a couple of months.  On the other hand, the drug can result in reduced incontinence and fewer urinary problems.<br />
 Cost can also be a problem. The pills cost $2 to $3 a day, or about $1,000 per year, and most insurers do not cover them for cancer prevention.<br />
 Speaking at the news conference, panel member Dr. Howard Sandler of Cedars-Sinai Medical Center said, &#8220;If I tried the medication for a month or two and I got some side effects, then for me personally the benefit wouldn&#8217;t be worth the risk.&#8221; But if there were no side effects, he added, &#8220;I might sleep better at night.&#8221;</p>
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